Grease and Vaseline: Microcrystalline wax is often used to manufacture hydrocarbon-based grease for instruments and sealing purposes, as well as thickeners for Vaseline-type products, due to its high gel strength, good adhesion, and excellent protective properties.

Pharmaceutical Ointments and Creams: As a hardening agent in topical creams and ointments, it can also reduce oil leakage from wax mixtures; with a higher melting point and greater melt viscosity than paraffin, it can increase the consistency of the formulation.