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https://www.creativebiomart.net/ctla4biotinylatedb7-2-inhibitor-screening-assay-kit-465598.htm
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https://www.creativebiomart.net/ctla4biotinylatedb7-2-inhibitor-screening-assay-kit-465598.htm
| Cat.No.: | Kit-1713 |
| Product Overview: | B7-2 (CD86) signaling through CTLA4(CD152) has been shown to inhibit T cell activation. This co-inhibitory pathway can be overactive in many tumors, enabling cancers to escape the host"s immune system. CTLA4-blocking antibodies, including Ipilimumab (Yervoy) and Tremelimumab, have shown clinical efficacy in treating cancer. |